How to set profile option from backend

Syntax:
FND_PROFILE.SAVE(<Profile_Option_Name>, <Profile_Option_Value>, <Level SITE/APPL/RESP/USER>, <Level_Value>, <Level_Value_App_id>);

FND_PROFILE.SAVE('P_NAME', 'P_VAL', 'SITE');
FND_PROFILE.SAVE('P_NAME', 'P_VAL', 'APPL', 321532);
FND_PROFILE.SAVE('P_NAME', 'P_VAL', 'RESP', 321532, 345234);
FND_PROFILE.SAVE('P_NAME', 'P_VAL', 'USER', 123321);